Cancer Immunology
Essentials

Masterful Antibodies: Checkpoint Blockade
Nils Lonberg and Alan J. Korman

Myeloid-Derived Suppressor Cells
George Plitas and Dmitry I. Gabrilovich

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy
Lorenzo Galluzzi, Laurence Zitvogel, and Guido Kroemer

Regulatory T Cells: Differentiation and Function
George Plitas and Alexander Y. Rudensky

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?
Ellen Puré and Albert Lo

Innate Lymphoid Cells in Cancer
Eric Vivier

Neoepitopes of Cancers: Looking Back, Looking Ahead
Pramod K. Srivastava

Pulling RANK on Cancer: Blocking Aire-Mediated Central Tolerance to Enhance Immunotherapy
Maureen A. Su and Mark S. Anderson

The Highs and Lows of Immune-Checkpoint Blockade in Lymphoma
Stephen M. Ansell

Adoptive Immunotherapy with Antigen-Specific T Cells Expressing a Native TCR
Wingchi Leung and Helen E. Heslop

Antibody–Cytokine Fusions: Versatile Products for the Modulation of Anticancer Immunity
Dario Neri

Revolutionizing Cancer Immunology: The Power of Next-Generation Sequencing Technologies
Meromit Singer and Ana C. Anderson

The Balancing Act between Cancer Immunity and Autoimmunity in Response to Immunotherapy
Arabella Young, Zoe Quandt and Jeffrey A. Bluestone

Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application
Nancy Tray, Jeffrey S. Weber and Sylvia Adams

T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection
Jonathan A. Trujillo, Randy F. Sweis, Riyue Bao and Jason J. Luke

Treg Fragility: A Prerequisite for Effective Antitumor Immunity?
Abigail E. Overacre-Delgoffe and Dario A.A. Vignali