Cancer Immunology
Essentials

Human Tumor Antigens Yesterday, Today, and Tomorrow
Olivera J. Finn

Masterful Antibodies: Checkpoint Blockade
Nils Lonberg and Alan J. Korman

Myeloid-Derived Suppressor Cells
George Plitas and Dmitry I. Gabrilovich

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy
Lorenzo Galluzzi, Laurence Zitvogel, and Guido Kroemer

Regulatory T Cells: Differentiation and Function
George Plitas and Alexander Y. Rudensky

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?
Ellen Puré and Albert Lo

Innate Lymphoid Cells in Cancer
Eric Vivier

Neoepitopes of Cancers: Looking Back, Looking Ahead
Pramod K. Srivastava

Gut Microbiota and Antitumor Immunity: Potential Mechanisms for Clinical Effect
Erez N. Baruch, Jingjing Wang and Jennifer A. Wargo

Fueling the Revolution: Targeting Metabolism to Enhance Immunotherapy
Robert D. Leone and Jonathan D. Powell

Lighting a Fire: Can We Harness Pyroptosis to Ignite Antitumor Immunity?
Zhibin Zhang, Ying Zhang and Judy Lieberman

Personal Neoantigen Cancer Vaccines: A Road Not Fully Paved
Edward F. Fritsch, Ute E. Burkhardt, Nir Hacohen and Catherine J. Wu

Insights into Tumor-Associated Tertiary Lymphoid Structures: Novel Targets for Antitumor Immunity and Cancer Immunotherapy
Anthony B. Rodriguez and Victor H. Engelhard

Understanding and Overcoming the Inflammatory Toxicities of Immunotherapy
Michael Dougan

Immune Escape during Breast Tumor Progression
Carlos R. Gil Del Alcazar, Maša Alečković and Kornelia Polyak

Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies
Dana L. Casey and Nai-Kong V. Cheung

Harnessing Natural Killer Cell Antitumor Immunity: From the Bench to Bedside
Karrune V. Woan and Jeffrey S. Miller

Metabolic Consequences of T-cell Costimulation in Anticancer Immunity
Alvaro Teijeira, Saray Garasa, Inaki Etxeberria, Maria Gato-Cañas, Ignacio Melero and Greg M. Delgoffe

Protective Innate Immune Variants in Racial/Ethnic Disparities of Breast and Prostate Cancer
Susan T. Yeyeodu, LaCreis R. Kidd and K. Sean Kimbro

Lessons Learned from Checkpoint Blockade Targeting PD-1 in Multiple Myeloma
Alexander M. Lesokhin, Susan Bal and Ashraf Z. Badros

Pulling RANK on Cancer: Blocking Aire-Mediated Central Tolerance to Enhance Immunotherapy
Maureen A. Su and Mark S. Anderson

The Highs and Lows of Immune-Checkpoint Blockade in Lymphoma
Stephen M. Ansell

Adoptive Immunotherapy with Antigen-Specific T Cells Expressing a Native TCR
Wingchi Leung and Helen E. Heslop