Must-Read 2018

This Cancer Immunology Research collection features the Journal's most-read pieces of content published in 2018. The featured articles were selected after taking into account online views and downloads of all papers published throughout the year. The pieces of content in this collection stood out in their respective category of article type, not only through the quantity of views and downloads they received, but through the pattern of online traffic to these articles. Interest was strong and sustained, showing that these may be of substantive, rather than fleeting, importance to our readers.

Cancer Immunology at the Crossroads

• T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection
  Trujillo JA…Luke JJ. Cancer Immunology Research September 2018.

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In the Spotlight

• Seeking Synergy of Checkpoint Blockade through TGFβ Inhibition
  Puré E. Cancer Immunology Research December 2018.
  
    ^*Editor's note: The research article that this "In the Spotlight" piece highlights follows below.
    This article was similarly highly viewed.
  
  • Stromal Fibroblasts Mediate Anti–PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma
    Zhao F…Hanks BA. Cancer Immunology Research December 2018.

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Cancer Immunology Miniatures

• Successful Treatment of HIV-Associated Kaposi Sarcoma with Immune Checkpoint Blockade
  Galanina N...Kurzrock R. Cancer Immunology Research October 2018.

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Priority Brief

• Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases
  Magee MS…Snook AE. Cancer Immunology Research May 2018.

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Research Article

• Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors
  Nirmal AJ...Freeman TC. Cancer Immunology Research November 2018.
• The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity
  Danilova L…Smith KN. Cancer Immunology Research August 2018.