Table 2.

Cell product characteristics

Cell compositionMedianRange
CD8+ (among CD3+ cells)36%7%–89%
Effector memory (among CD8+ cells)51%39%–73%
Effector memory (among CD4+ cells)48%32%–76%
Central memory (among CD8+ cells)36%4%–59%
Central memory (among CD4+ cells)34%20%–53%
Vector copy number/cell0.610.37–1.86
NKG2D CAR+ (among CD8+)66%15%–87%
NKG2D CAR+ (among CD4+)92%74%–98%
NKG2D CAR+ (among CD3+)75%55%–90%
# of transduced viable T cells infused
Dose level 17.38 × 10e57.35–7.95
Dose level 22.15 × 10e61.64–2.67
Dose level 36.92 × 10e66.31–7.54
Dose level 42.45 × 10e72.28–2.70
  • NOTE: Effector memory (CD45RO+, CCR7), central memory (CD45RO+, CCR7+).