Table 1.

Univariate and multivariate analysis for OS in two cohorts of gastric cancer patients

Univariate analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P valueScore
TC PD-L1
 Positive110
 Negative2.474 (1.449–4.224)0.0011.841 (1.044–3.246)0.0351
IC PD-L1
 Negative110
 Positive1.944 (1.165–3.243)0.0113.156 (1.775–5.611)0.0000912
IC PD-1
 Negative110
 Positive2.236 (1.405–3.559)0.0012.354 (1.437–3.859)0.0011
CD8
 More110
 Less1.513 (0.928–2.465)0.0971.72 (1–2.96)0.051
Lauren classification
 Intestinal type110
 Diffuse type2.099 (1.208–3.648)0.0091.747 (1.237–2.466)0.0021
 Mix2.838 (1.382–5.826)0.0041.747 (1.237–2.466)0.0021
Differentiation
 Well1
 Moderate1.199 (0.39–3.682)0.751
 Poor2.215 (0.802–6.118)0.125
AJCC stage
 2110
 34.778 (1.916–11.917)0.0015.496 (2.124–14.218)0.0004423
  • Abbreviations: CI, confidence interval; HR, hazard ratio; IC, immune cell; TC, tumor cell.