Table 1

Human CT (Cancer/Testis) Antigens.

CTa System # Genes Chromosome Location Detection Systemb References
1 MAGE 16 Xq28/Xp21 T, Ab 7,10,12,13
2 BAGE 2 Unknown T 14
3 GAGE 9 Xp11 T 15,16
4 SSX >5 Xp11 Ab 10,17
5 NY-ESO-1LAGE-1 2 Xq28 Ab, T, RDA 18,19
6 SCP-1 3 1p12-p13 Ab 20
7 CT7 / MAGE-C1 1 Xq26 Ab, RDA 21,22
8 CT8 1 Unknown Ab 23
9 CT9 1 1p Ab 24
10 CT10 / MAGE-C2 1 Xq27 RDA, Ab 25,26
11 CTp11 1 Xq26 -Xq27 -c 27
12 SAGE 1 Xq28 RDA 28
13 cTAGE-1 1 18p11 Ab 29
14 OY-TES-1 2 12p12-p13 Ab 30

aNumbered according to the CT nomenclature proposed by Old & Chen (11). bAbbreviations: Ab, antibody; T, CD8+ T cell; RDA, representational difference analysis. cDefined by differential mRNA expression in a parental vs. metastatic melanoma cell variant.