SEREX-defined breast cancer antigens: Antigens detected with sera from a single breast cancer patient1.
| NY-BR-Antigen | Identity/Similarities/Motifs (Unigene cluster) | NY-BR-Antigen | Identity/Similarities/Motifs (Unigene cluster) |
| Known Gene Products | |||
| 10 | Desmoplakin I (Hs.74316) | 48 | Sorting nexin 6 (Hs.76127) |
| 11 | RING 3 gene product (Hs.75243) | 52 | Transcriptional activator SRCAP (Hs.87908) |
| 19 | CGI-149 protein (Hs.241266) | 54 | SOM172 gene product (Hs.100623) |
| 21 | KIAA0708 (Hs.117177) | 67 | TIS11D gene product (Hs.78909) |
| 26 | Modulator recognition factor (Hs.920) | 76 | MAGE A3 (Hs. 36978) |
| 33 | GSPT1 (Hs.2707) | 77 | SMRT corepressor (Hs.120980) |
| 37 | HRIHFB2157 gene product (Hs.4552) | 83 | KIAA0081 protein, (Hs.78871) |
| 44 | BMAL1e protein (Hs.74515) | 92 | Ribosomal protein L10 (Hs. 29797) |
| Novel Gene Products | |||
| 38 | SCR repeat domain (not clustered) | 73 | Similar to coatomer proteins (Hs.217001) |
| 46 | None (not clustered) | 85 | Nuclear localization signals (Hs.105153) |
| 49 | Ankyrin repeat domain (Hs.55565) | 84 | Transmembrane domain (Hs.206196) |
| 51 | None (Hs.128685) | 99 | RNA splicing factors similarity (Hs.183438) |
1Antigens reacted with sera from single breast cancer patients (1/25), but not with sera from normal individuals (0/25), colon cancer patients (0/19), lung cancer patients (0/15), ovarian cancer patients (0/15) or esophageal cancer patients (0/15), and no equivalent isolates of these antigens were found in the SEREX database.