Table 1

Immunoscreening of cDNA expression libraries from breast cancer with autologous and allogeneic patient sera (SEREX).

Tumor Type Serum Source Breast Cancer cDNA Library Designation Number of Distinct Antigens Identified by SEREX(Known1/Novel2) Antigens with Non-Cancer Related Serological Profiles Antigens with Cancer-related Serological Profiles
Invasive ductal carcinoma Autologous 184 17 (12/5) 13 4
Invasive ductal carcinoma Autologous 297 6 (6/0) 5 1
Invasive ductal carcinoma Autologous 257 9 (8/1) 4 5
Invasive pleomorphic lobular carcinoma Autologous 263 13 (9/4) 5 8
SK-BR-3 (established breast cancer cell line) Allogeneic-1 9993 34 (27/7) 14 20
SK-BR-3 Allogeneic-2 9993 15 (12/3) 9 6
Totals 94 (74/20) 50 44

1Identical to GenBank Entries. 2Identities limited to expressed sequence tags (ESTs).