Immunoscreening of cDNA expression libraries from breast cancer with autologous and allogeneic patient sera (SEREX).
Tumor Type | Serum Source | Breast Cancer cDNA Library Designation | Number of Distinct Antigens Identified by SEREX(Known1/Novel2) | Antigens with Non-Cancer Related Serological Profiles | Antigens with Cancer-related Serological Profiles |
Invasive ductal carcinoma | Autologous | 184 | 17 (12/5) | 13 | 4 |
Invasive ductal carcinoma | Autologous | 297 | 6 (6/0) | 5 | 1 |
Invasive ductal carcinoma | Autologous | 257 | 9 (8/1) | 4 | 5 |
Invasive pleomorphic lobular carcinoma | Autologous | 263 | 13 (9/4) | 5 | 8 |
SK-BR-3 (established breast cancer cell line) | Allogeneic-1 | 9993 | 34 (27/7) | 14 | 20 |
SK-BR-3 | Allogeneic-2 | 9993 | 15 (12/3) | 9 | 6 |
Totals | 94 (74/20) | 50 | 44 |
1Identical to GenBank Entries. 2Identities limited to expressed sequence tags (ESTs).