Table 3.

Association between T-bet+ and IHC markers

T-bet−/lowT-bet+/high
(n = 566)a(n = 48)a
MarkeraNumber (%)Number (%)Pb
HER2
 Negative500 (92.1)44 (93.6)1.0000
 Positive43 (7.9)3 (6.4)
ER
 Negative129 (25.7)30 (73.2)<0.0001
 Positive373 (74.3)11 (26.8)
PgR
 Negative217 (41.6)34 (81.0)<0.0001
 Positive305 (58.4)8 (19.0)
p53
 Negative417 (77.5)24 (50.0)0.0001
 Positive121 (22.5)24 (50.0)
EGFR
 Negative489 (94.6)30 (65.2)<0.0001
 Positive28 (5.4)16 (34.8)
CK5
 Negative459 (85.8)21 (44.7)<0.0001
 Positive76 (14.2)26 (55.3)
Ki-67
 <14%181 (40.9)2 (4.8)<0.0001
 ≥14%262 (59.1)40 (95.2)
  • aIHC marker data are not available for some tumors.

  • bBy Fisher exact test.