Demographics and clinical characteristics
Characteristics | With irAE (n = 46) | Without irAE (n = 101) | Total (N = 147) | P |
---|---|---|---|---|
Sex | ||||
Male | 25 | 63 | 88 | 0.37 |
Female | 21 | 38 | 59 | |
Median age (years) | 65.0 | 64.0 | 64.5 | 0.81 |
Race | ||||
White | 43 | 85 | 128 | 0.18 |
Nonwhite | 3 | 16 | 19 | |
Smoking | ||||
Never | 22 | 47 | 69 | 0.92 |
Former | 22 | 47 | 69 | |
Current | 2 | 7 | 9 | |
ECOG performance status | ||||
0 | 33 | 71 | 104 | 0.24 |
1 | 9 | 25 | 34 | |
2 | 3 | 1 | 4 | |
Unknown | 1 | 4 | 5 | |
Median duration of ipilimumab therapy (months) | 8.9 | 8.0 | 8.1 | 0.61 |