Table 1.

Patient baseline characteristics

All patients (n = 34)
GenderN (%)
 Male19 (56)
 Female15 (54)
Age, median (range)58 (32–79)
ECOG performance status
 014
 120
Carcinomas (n = 23)
GenderN (%)
 Male1 (4)
 Female22 (96)
Age, median (range)52 (32–79)
Tumor typeN (%)
 Colorectal11 (32)
 Chordoma11 (32)
 Breast5 (15)
 Pancreatic3 (9)
 Prostate2 (6)
 Urothelial1 (3)
 Lung1 (3)
Disease at study entryN (%)
 Stable disease1 (4)
 Progressive disease22 (96)
Prior cytotoxic regimens
 01
 12
 28
 ≥312
Chordoma (n = 11)
GenderN (%)
 Male10 (91)
 Female1 (9)
Age, median (range)58.5 (32–66)
Tumor anatomical location
 Sacral6 (55)
 Clival3 (27)
 Spinal2 (18)
Disease at study entryN (%)
 Stable disease2 (18)
 Progressive disease9 (82)
Prior therapyN (%)
 Surgery11 (100)
 Radiotherapy11 (100)
 Systemic therapy5 (45)