Table 1.

Male CARD9-deficient APCmin mice have improved viability

GenotypeFemalesMalesTotal
+/+6/16 (37.5%)15/17 (88.2%)21/33 (63.6%)
−/−10/16 (62.5%)2/17 (11.8%)12/33 (36.4%)
P0.50.0020.2

NOTE: Mice of indicated sex and Card9 status were counted upon reaching the humane endpoint or mortality. P value was determined by binomial test of the null hypothesis that genotype did not affect mouse viability.