Table 2.

Epithelial and stromal PD-L1 expression association with Yale neoadjuvant cohort characteristics

P value
CharacteristicTumor maskStroma
Age (y)
 <500.30360.4228
 ≥50
Nodal status
 Positive0.30620.3811
 Negative
Tumor size (cm)
 <20.47080.8819
 >2
Estrogen receptor
 Negative0.0378a0.0219a
 Positive
Progesterone receptor
 Negative0.0099a0.0009a
 Positive
HER2
 Negative0.73810.7826
 Positive
Triple-negative
 Yes0.0026b0.0021b
 No
LPBC
 Yes<0.0001b<0.0001b
 No
  • aNegative association with PD-L1.

  • bPositive association with PD-L1.