Table 2.

Multivariate analysis of clinicopathologic and immune characteristics for survival and recurrence

OSTTR
VariablesHR (95% CI)PHR (95% CI)P
Model 1
 Minor resection (<3 segments)0.62 (0.39–0.98)0.04NS
 Negative margin0.30 (0.15–0.60)0.001NS
 Solitary hepatic metastasisNSNS
 Size of largest tumor ≤5 cm0.47 (0.29–0.76)0.002NS
 Preoperative CEA ≤200 ng/mL0.50 (0.29–0.85)0.010.46 (0.27–0.78)0.004
 Node-negative primary0.38 (0.24–0.62)<0.0010.52 (0.33–0.81)0.004
 DFI >12 moNSNS
 MHC-IhiCD3hi0.36 (0.20–0.67)0.0010.54 (0.29–0.98)0.046
Model 2
 Clinical risk score <30.37 (0.25–0.55)<0.0010.43 (0.28–0.64)<0.001
 MHC-IhiCD3hi0.45 (0.26–0.79)0.0050.52 (0.29–0.94)0.031

NOTE: Forward selection stepwise multivariate Cox regression.

Abbreviation: NS, not statistically significant.