RT Journal Article SR Electronic T1 Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy JF Cancer Immunity Archive JO Cancer Immun FD American Association for Cancer Research SP 1 VO 10 IS 1 A1 Yuan, Jianda A1 Page, David B. A1 Ku, Geoffrey Y. A1 Li, Yanyun A1 Mu, Zhenyu A1 Ariyan, Charlotte A1 Gallardo, Humilidad F. A1 Roman, Ruth-Ann A1 Heine, Agnes I. A1 Terzulli, Stephanie L. A1 Ritter, Erika A1 Gnjatic, Sacha A1 Ritter, Gerd A1 Jungbluth, Achim A. A1 Allison, James P. A1 Old, Lloyd J. A1 Wolchok, Jedd D. YR 2010 UL http://cancerimmunolres.aacrjournals.org/content/10/1/1.abstract AB Melanoma patients treated with anti-CTLA-4 have shown a range of anti-tumor responses. In this report, we describe the response of a single patient to anti-CTLA-4, with individual lesions disappearing, others stabilizing, and others progressing. These responses can be viewed as a clear manifestation of cancer immunoediting and its three phases of elimination, equilibrium and escape, with each tumor in this patient being at a discrete stage in the process. The patient's course and associated immunological monitoring and other laboratory data are presented in an immunogram, a way to visualize temporal associations between the multiple clinical and laboratory parameters.This article was published in Cancer Immunity, a Cancer Research Institute journal that ceased publication in 2013 and is now provided online in association with Cancer Immunology Research.