PT - JOURNAL ARTICLE AU - Yuan, Jianda AU - Page, David B. AU - Ku, Geoffrey Y. AU - Li, Yanyun AU - Mu, Zhenyu AU - Ariyan, Charlotte AU - Gallardo, Humilidad F. AU - Roman, Ruth-Ann AU - Heine, Agnes I. AU - Terzulli, Stephanie L. AU - Ritter, Erika AU - Gnjatic, Sacha AU - Ritter, Gerd AU - Jungbluth, Achim A. AU - Allison, James P. AU - Old, Lloyd J. AU - Wolchok, Jedd D. TI - Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy DP - 2010 Jan 01 TA - Cancer Immunity Archive PG - 1 VI - 10 IP - 1 4099 - http://cancerimmunolres.aacrjournals.org/content/10/1/1.short 4100 - http://cancerimmunolres.aacrjournals.org/content/10/1/1.full SO - Cancer Immun2010 Jan 01; 10 AB - Melanoma patients treated with anti-CTLA-4 have shown a range of anti-tumor responses. In this report, we describe the response of a single patient to anti-CTLA-4, with individual lesions disappearing, others stabilizing, and others progressing. These responses can be viewed as a clear manifestation of cancer immunoediting and its three phases of elimination, equilibrium and escape, with each tumor in this patient being at a discrete stage in the process. The patient's course and associated immunological monitoring and other laboratory data are presented in an immunogram, a way to visualize temporal associations between the multiple clinical and laboratory parameters.This article was published in Cancer Immunity, a Cancer Research Institute journal that ceased publication in 2013 and is now provided online in association with Cancer Immunology Research.