Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Cancer Immunology Essentials
    • Collections
      • COVID-19 & Cancer Resource Center
      • "Best of" Collection
      • Editors' Picks
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Cancer Immunology Research
Cancer Immunology Research
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Cancer Immunology Essentials
    • Collections
      • COVID-19 & Cancer Resource Center
      • "Best of" Collection
      • Editors' Picks
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Articles

Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer

Nana E. Tchabo, Paulette Mhawech-Fauceglia, Otavia L. Caballero, Jeannine Villella, Amy F. Beck, Anthony J. Miliotto, Jianqun Liao, Christopher Andrews, Shashikant Lele, Lloyd J. Old and Kunle Odunsi
Nana E. Tchabo
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paulette Mhawech-Fauceglia
2Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Otavia L. Caballero
3Ludwig Institute for Cancer Research, New York Branch of Human Cancer Immunology at Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeannine Villella
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Amy F. Beck
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anthony J. Miliotto
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jianqun Liao
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christopher Andrews
4Department of Biostatistics, University at Buffalo, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shashikant Lele
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lloyd J. Old
3Ludwig Institute for Cancer Research, New York Branch of Human Cancer Immunology at Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kunle Odunsi
1Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
5Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI:  Published January 2009
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Figures & Data

Figures

  • Figure 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1

    RT-PCR analysis for PLAC1 and DPPA2 expression in a normal tissue panel. (A) PLAC1 mRNA expression yielded a 328 bp product. (B) DPPA2 mRNA expression yielded a 430 bp product. (C) GAPDH (glyceraldehyde-3-phosphate dehydrogenase) served as an endogenous control and yielded a 204 bp product. Lanes: M, marker; 1, blank; 2, placenta; 3, adrenal gland; 4, bone marrow; 5, brain; 6, cerebellum; 7, fetal liver; 8, fetal brain; 9, heart; 10, placenta; 11, prostate; 12, testis.

  • Table 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Table 1

    Patient characteristics.

  • Figure 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2

    RT-PCR analysis for PLAC1 expression in a subset of ovarian cancer specimens.PLAC1 mRNA expression yielded a 328 bp product. GAPDH (glyceraldehyde-3-phosphate dehydrogenase) served as an endogenous control and yielded a 204 bp product. Shown is mRNA from placenta (lane 1). Lanes 2, 4, 6, and 7 are positive for PLAC1 mRNA expression whereas lanes 3, 8, and 9 are negative. Lane 5 has a negative GAPDH control and hence PLAC1 mRNA expression in this specimen is inconclusive.

  • Figure 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3

    DPPA2 expression in testis and an ovarian tumor specimen. Immunohistochemical staining was carried out with a polyclonal rabbit anti-DPPA2 antibody. (A) The spermatocytes of the normal testis show a nuclear pattern of staining of strong intensity. (B) Staining of an ovarian tumor specimen.

  • Figure 4
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 4

    Serological reactivity of the recombinant PLAC1 protein in a subset of ovarian cancer patients. The presence of anti-PLAC1 antibodies in serum samples was assessed by ELISA. Serum obtained from a healthy donor (#00100212) was used as a known positive control.

  • Figure 5
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 5

    Serological reactivity of the recombinant DPPA2 protein in a subset of ovarian cancer patients. The presence of anti-DPPA2 antibodies in serum samples was assessed by ELISA. Serum obtained from a seropositive NY-ESO-1 patient (SRM13) was used as a positive control and that obtained from a seronegative NY-ESO-1 patient (SRM24) was used as a negative control. Sera #15559, #15555, and #15418 tested negative for DPPA2 expression by RT-PCR.

PreviousNext
Back to top
Cancer Immunity Archive: 9 (1)
January 2009
Volume 9, Issue 1
  • Table of Contents

Sign up for alerts

View this article with LENS

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Cancer Immunology Research article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer
(Your Name) has forwarded a page to you from Cancer Immunology Research
(Your Name) thought you would be interested in this article in Cancer Immunology Research.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer
Nana E. Tchabo, Paulette Mhawech-Fauceglia, Otavia L. Caballero, Jeannine Villella, Amy F. Beck, Anthony J. Miliotto, Jianqun Liao, Christopher Andrews, Shashikant Lele, Lloyd J. Old and Kunle Odunsi
Cancer Immun January 1 2009 (9) (1) 6;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer
Nana E. Tchabo, Paulette Mhawech-Fauceglia, Otavia L. Caballero, Jeannine Villella, Amy F. Beck, Anthony J. Miliotto, Jianqun Liao, Christopher Andrews, Shashikant Lele, Lloyd J. Old and Kunle Odunsi
Cancer Immun January 1 2009 (9) (1) 6;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Results
    • Discussion
    • Materials and methods
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

More in this TOC Section

  • NY-ESO-1–specific immunological pressure and escape in a patient with metastatic melanoma
  • Hsp72 mediates stronger antigen-dependent non-classical MHC class Ib anti-tumor responses than hsc73 in Xenopus laevis
  • Human ovarian tumor ascites fluids rapidly and reversibly inhibit T cell receptor-induced NF-κB and NFAT signaling in tumor-associated T cells
Show more Articles
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook   Twitter   LinkedIn   YouTube   RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Cancer Immunology Essentials

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Cancer Immunology Research

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Cancer Immunology Research
eISSN: 2326-6074
ISSN: 2326-6066

Advertisement