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Abstract
Adoptive T-cell therapy requires the transferred lymphocytes to adapt to the hypoxic tumor microenvironment. In this issue, Veliça and colleagues found that modified HIF2α expression in CD8+ T cells increases antitumor efficacy.
See article by Veliça et al., p. 401
Footnotes
Cancer Immunol Res 2021;9:364
- ©2021 American Association for Cancer Research.
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April 2021
Volume 9, Issue 4
Volume 9, Issue 4
HIF1α or HIF2α: Enhancing CD8+ T-cell Fitness for Antitumor Immunity
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