Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer

Marie-Claire Wagle; Joseph Castillo; Shrividhya Srinivasan; Thomas Holcomb; Kobe C. Yuen; Edward E. Kadel; Sanjeev Mariathasan; Daniel L. Halligan; Adrian R. Carr; Max Bylesjo; Paul R. McAdam; Sarah Lynagh; Koen M. Marien; Mark Kockx; Yannick Waumans; Shih-Min A. Huang; Mark R. Lackner; Zineb Mounir

doi:10.1158/2326-6066.CIR-19-0568

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Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer

Marie-Claire Wagle, Joseph Castillo, Shrividhya Srinivasan, Thomas Holcomb, Kobe C. Yuen, Edward E. Kadel, Sanjeev Mariathasan, Daniel L. Halligan, Adrian R. Carr, Max Bylesjo, Paul R. McAdam, Sarah Lynagh, Koen M. Marien, Mark Kockx, Yannick Waumans, Shih-Min A. Huang, Mark R. Lackner and Zineb Mounir

Marie-Claire Wagle

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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For correspondence: zineb.mounir@mail.mcgill.ca mariewagle@gmail.com

Joseph Castillo

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Shrividhya Srinivasan

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Thomas Holcomb

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Kobe C. Yuen

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Edward E. Kadel

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Sanjeev Mariathasan

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Daniel L. Halligan

2Fios Genomics, Nine Edinburgh Bioquarter, Edinburgh, United Kingdom.

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Adrian R. Carr

2Fios Genomics, Nine Edinburgh Bioquarter, Edinburgh, United Kingdom.

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Max Bylesjo

2Fios Genomics, Nine Edinburgh Bioquarter, Edinburgh, United Kingdom.

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Paul R. McAdam

2Fios Genomics, Nine Edinburgh Bioquarter, Edinburgh, United Kingdom.

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Sarah Lynagh

2Fios Genomics, Nine Edinburgh Bioquarter, Edinburgh, United Kingdom.

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Koen M. Marien

3HistoGeneX, Antwerp, Belgium.

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Mark Kockx

3HistoGeneX, Antwerp, Belgium.

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Yannick Waumans

3HistoGeneX, Antwerp, Belgium.

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Shih-Min A. Huang

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Mark R. Lackner

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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Zineb Mounir

1Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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For correspondence: zineb.mounir@mail.mcgill.ca mariewagle@gmail.com

DOI: 10.1158/2326-6066.CIR-19-0568 Published July 2020

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July 2020
Volume 8, Issue 7

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Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer