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Cancer Immunology Research
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Pharmacologic Inhibition of FGFR Modulates the Metastatic Immune Microenvironment and Promotes Response to Immune Checkpoint Blockade

Saeed S. Akhand, Zian Liu, Stephen C. Purdy, Ammara Abdullah, Hang Lin, Gregory M. Cresswell, Timothy L. Ratliff and Michael Wendt
Saeed S. Akhand
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
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Zian Liu
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
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  • ORCID record for Zian Liu
Stephen C. Purdy
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
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Ammara Abdullah
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
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  • ORCID record for Ammara Abdullah
Hang Lin
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
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Gregory M. Cresswell
2Department of Comparative Pathobiology, Purdue University, West Lafayette, Indiana.
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  • ORCID record for Gregory M. Cresswell
Timothy L. Ratliff
2Department of Comparative Pathobiology, Purdue University, West Lafayette, Indiana.
3Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana.
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Michael Wendt
1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
3Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana.
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  • For correspondence: mwendt@purdue.edu
DOI: 10.1158/2326-6066.CIR-20-0235 Published December 2020
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Cited By

Article Information

Volume 8, Issue 12, pp. 1542-1553

DOI 
https://doi.org/10.1158/2326-6066.CIR-20-0235
PubMed 
33093218

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received March 26, 2020
  • Revision received July 7, 2020
  • Accepted October 14, 2020
  • Published first October 22, 2020.

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  • Previous version (October 22, 2020 - 06:11).
  • Previous version (November 11, 2020 - 06:00).
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©2020 American Association for Cancer Research.

Author Information

  1. Saeed S. Akhand1,
  2. Zian Liu1,
  3. Stephen C. Purdy1,
  4. Ammara Abdullah1,
  5. Hang Lin1,
  6. Gregory M. Cresswell2,
  7. Timothy L. Ratliff2,3, and
  8. Michael Wendt1,3,*
  1. 1Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
  2. 2Department of Comparative Pathobiology, Purdue University, West Lafayette, Indiana.
  3. 3Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana.
  1. ↵*Corresponding Author:
    Michael Wendt, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 201 South University Street, Hansen Life Sciences Building, West Lafayette, IN 47907. Phone: 765-494-0860; Fax: 765-494-1414; E-mail: mwendt{at}purdue.edu
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Cancer Immunology Research: 8 (12)
December 2020
Volume 8, Issue 12
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Pharmacologic Inhibition of FGFR Modulates the Metastatic Immune Microenvironment and Promotes Response to Immune Checkpoint Blockade
Saeed S. Akhand, Zian Liu, Stephen C. Purdy, Ammara Abdullah, Hang Lin, Gregory M. Cresswell, Timothy L. Ratliff and Michael Wendt
Cancer Immunol Res December 1 2020 (8) (12) 1542-1553; DOI: 10.1158/2326-6066.CIR-20-0235

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Pharmacologic Inhibition of FGFR Modulates the Metastatic Immune Microenvironment and Promotes Response to Immune Checkpoint Blockade
Saeed S. Akhand, Zian Liu, Stephen C. Purdy, Ammara Abdullah, Hang Lin, Gregory M. Cresswell, Timothy L. Ratliff and Michael Wendt
Cancer Immunol Res December 1 2020 (8) (12) 1542-1553; DOI: 10.1158/2326-6066.CIR-20-0235
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