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Cancer Immunology Research
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Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling

Jimin Son, Jae-Won Cho, Hyo Jin Park, Jihyun Moon, Seyeon Park, Hoyoung Lee, Jeewon Lee, Gamin Kim, Su-Myeong Park, Sergio A. Lira, Andrew N. Mckenzie, Hye Young Kim, Cheol Yong Choi, Yong Taik Lim, Seong Yong Park, Hye Ryun Kim, Su-Hyung Park, Eui-Cheol Shin, Insuk Lee and Sang-Jun Ha
Jimin Son
1Department of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
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  • ORCID record for Jimin Son
Jae-Won Cho
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
3Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
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Hyo Jin Park
1Department of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
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  • ORCID record for Hyo Jin Park
Jihyun Moon
1Department of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
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Seyeon Park
1Department of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
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Hoyoung Lee
4Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea.
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Jeewon Lee
4Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea.
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Gamin Kim
5Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Su-Myeong Park
5Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Sergio A. Lira
6Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
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Andrew N. Mckenzie
7Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.
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Hye Young Kim
8Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
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Cheol Yong Choi
9Department of Biological Sciences, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea.
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Yong Taik Lim
10SKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea.
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Seong Yong Park
11Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Hye Ryun Kim
5Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Su-Hyung Park
4Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea.
12Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
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Eui-Cheol Shin
4Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea.
12Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
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Insuk Lee
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
3Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
13Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.
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  • For correspondence: sjha@yonsei.ac.kr insuklee@yonsei.ac.kr
Sang-Jun Ha
1Department of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea.
2Brain Korea 21 (BK21) PLUS Program, Initiative for Biological Functions & Systems, Yonsei University, Seoul, Republic of Korea.
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  • For correspondence: sjha@yonsei.ac.kr insuklee@yonsei.ac.kr
DOI: 10.1158/2326-6066.CIR-19-0828 Published November 2020
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Cancer Immunology Research: 8 (11)
November 2020
Volume 8, Issue 11
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Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling
Jimin Son, Jae-Won Cho, Hyo Jin Park, Jihyun Moon, Seyeon Park, Hoyoung Lee, Jeewon Lee, Gamin Kim, Su-Myeong Park, Sergio A. Lira, Andrew N. Mckenzie, Hye Young Kim, Cheol Yong Choi, Yong Taik Lim, Seong Yong Park, Hye Ryun Kim, Su-Hyung Park, Eui-Cheol Shin, Insuk Lee and Sang-Jun Ha
Cancer Immunol Res November 1 2020 (8) (11) 1393-1406; DOI: 10.1158/2326-6066.CIR-19-0828

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Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling
Jimin Son, Jae-Won Cho, Hyo Jin Park, Jihyun Moon, Seyeon Park, Hoyoung Lee, Jeewon Lee, Gamin Kim, Su-Myeong Park, Sergio A. Lira, Andrew N. Mckenzie, Hye Young Kim, Cheol Yong Choi, Yong Taik Lim, Seong Yong Park, Hye Ryun Kim, Su-Hyung Park, Eui-Cheol Shin, Insuk Lee and Sang-Jun Ha
Cancer Immunol Res November 1 2020 (8) (11) 1393-1406; DOI: 10.1158/2326-6066.CIR-19-0828
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