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Cancer Immunology Research
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Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma

Tatiana Pazina, Ashley M. James, Kimberly B. Colby, Yibin Yang, Andrew Gale, Amy Jhatakia, Alper Y. Kearney, Robert F. Graziano, Natalie A. Bezman, Michael D. Robbins, Adam D. Cohen and Kerry S. Campbell
Tatiana Pazina
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
2FSBSI “Institute of Experimental Medicine,” St. Petersburg, Russia.
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Ashley M. James
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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Kimberly B. Colby
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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Yibin Yang
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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Andrew Gale
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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Amy Jhatakia
3Bristol-Myers Squibb, Princeton, New Jersey.
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Alper Y. Kearney
3Bristol-Myers Squibb, Princeton, New Jersey.
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Robert F. Graziano
3Bristol-Myers Squibb, Princeton, New Jersey.
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Natalie A. Bezman
3Bristol-Myers Squibb, Princeton, New Jersey.
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Michael D. Robbins
3Bristol-Myers Squibb, Princeton, New Jersey.
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Adam D. Cohen
4Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.
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  • For correspondence: kerry.campbell@fccc.edu adam.cohen@uphs.upenn.edu
Kerry S. Campbell
1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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  • For correspondence: kerry.campbell@fccc.edu adam.cohen@uphs.upenn.edu
DOI: 10.1158/2326-6066.CIR-18-0579 Published October 2019
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Total3228729765

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Article Information

Volume 7, Issue 10, pp. 1633-1646

DOI 
https://doi.org/10.1158/2326-6066.CIR-18-0579
PubMed 
31431433

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received August 22, 2018
  • Revision received March 5, 2019
  • Accepted August 13, 2019
  • Published first August 20, 2019.

Article Versions

  • Previous version (August 20, 2019 - 06:23).
  • Previous version (September 13, 2019 - 05:46).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Tatiana Pazina1,2,
  2. Ashley M. James1,
  3. Kimberly B. Colby1,
  4. Yibin Yang1,
  5. Andrew Gale1,
  6. Amy Jhatakia3,
  7. Alper Y. Kearney3,
  8. Robert F. Graziano3,
  9. Natalie A. Bezman3,
  10. Michael D. Robbins3,
  11. Adam D. Cohen4,*, and
  12. Kerry S. Campbell1,*
  1. 1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  2. 2FSBSI “Institute of Experimental Medicine,” St. Petersburg, Russia.
  3. 3Bristol-Myers Squibb, Princeton, New Jersey.
  4. 4Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.
  1. ↵*Corresponding Authors:
    Kerry S. Campbell, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111. Phone: 215-728-7761; Fax: 215-728-2412; E-mail: kerry.campbell{at}fccc.edu; and Adam D. Cohen, Abramson Cancer Center at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104. Phone: 215-615-5853; E-mail: adam.cohen{at}uphs.upenn.edu
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Cancer Immunology Research: 7 (10)
October 2019
Volume 7, Issue 10
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Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma
Tatiana Pazina, Ashley M. James, Kimberly B. Colby, Yibin Yang, Andrew Gale, Amy Jhatakia, Alper Y. Kearney, Robert F. Graziano, Natalie A. Bezman, Michael D. Robbins, Adam D. Cohen and Kerry S. Campbell
Cancer Immunol Res October 1 2019 (7) (10) 1633-1646; DOI: 10.1158/2326-6066.CIR-18-0579

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Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma
Tatiana Pazina, Ashley M. James, Kimberly B. Colby, Yibin Yang, Andrew Gale, Amy Jhatakia, Alper Y. Kearney, Robert F. Graziano, Natalie A. Bezman, Michael D. Robbins, Adam D. Cohen and Kerry S. Campbell
Cancer Immunol Res October 1 2019 (7) (10) 1633-1646; DOI: 10.1158/2326-6066.CIR-18-0579
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