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Cancer Immunology Research
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Research Articles

Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer

Jieru Zhou, Xiaoduan Li, Xiaoli Wu, Ting Zhang, Qinyi Zhu, Xinjing Wang, Husheng Wang, Kai Wang, Yingying Lin and Xipeng Wang
Jieru Zhou
1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Xiaoduan Li
2Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
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Xiaoli Wu
1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Ting Zhang
3Center for Reproductive Medicine, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Renji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China.
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Qinyi Zhu
2Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
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Xinjing Wang
1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Husheng Wang
1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Kai Wang
2Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
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Yingying Lin
4Department of Neurosurgery, RenJi Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
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  • For correspondence: wangxipeng@xinhuamed.com.cn yylin@sibs.ac.cn
Xipeng Wang
1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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  • For correspondence: wangxipeng@xinhuamed.com.cn yylin@sibs.ac.cn
DOI: 10.1158/2326-6066.CIR-17-0479 Published December 2018
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Article Information

Volume 6, Issue 12, pp. 1578-1592

DOI 
https://doi.org/10.1158/2326-6066.CIR-17-0479
PubMed 
30396909

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received August 31, 2017
  • Revision received February 22, 2018
  • Accepted October 29, 2018
  • Published first November 5, 2018.

Article Versions

  • Previous version (November 5, 2018 - 07:20).
  • Previous version (November 19, 2018 - 10:48).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2018 American Association for Cancer Research.

Author Information

  1. Jieru Zhou1,
  2. Xiaoduan Li2,
  3. Xiaoli Wu1,
  4. Ting Zhang3,
  5. Qinyi Zhu2,
  6. Xinjing Wang1,
  7. Husheng Wang1,
  8. Kai Wang2,
  9. Yingying Lin4,*, and
  10. Xipeng Wang1,*
  1. 1Department of Obstetrics and Gynaecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  2. 2Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
  3. 3Center for Reproductive Medicine, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Renji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China.
  4. 4Department of Neurosurgery, RenJi Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
  1. ↵*Corresponding Authors:
    Xipeng Wang, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Department of Obstetrics and Gynecology, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang RD, Yangpu district, Shanghai, 200092, China. Phone: 86-13817806602; E-mail: wangxipeng{at}xinhuamed.com.cn; and Yingying Lin, Phone: 86-15800727180; Fax: 86-21-68383982; E-mail: yylin{at}sibs.ac.cn
  1. J. Zhou, X. Li, and X. Wu contributed equally to this article.

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Cancer Immunology Research: 6 (12)
December 2018
Volume 6, Issue 12
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Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer
Jieru Zhou, Xiaoduan Li, Xiaoli Wu, Ting Zhang, Qinyi Zhu, Xinjing Wang, Husheng Wang, Kai Wang, Yingying Lin and Xipeng Wang
Cancer Immunol Res December 1 2018 (6) (12) 1578-1592; DOI: 10.1158/2326-6066.CIR-17-0479

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Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer
Jieru Zhou, Xiaoduan Li, Xiaoli Wu, Ting Zhang, Qinyi Zhu, Xinjing Wang, Husheng Wang, Kai Wang, Yingying Lin and Xipeng Wang
Cancer Immunol Res December 1 2018 (6) (12) 1578-1592; DOI: 10.1158/2326-6066.CIR-17-0479
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