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Research Articles

Maelstrom Directs Myeloid-Derived Suppressor Cells to Promote Esophageal Squamous Cell Carcinoma Progression via Activation of the Akt1/RelA/IL8 Signaling Pathway

Pupu Li, Xinfeng Chen, Guohui Qin, Dongli Yue, Zhen Zhang, Yu Ping, Dan Wang, Xuan Zhao, Mengjia Song, Qitai Zhao, Jieyao Li, Shasha Liu, Dong Wang, Chaoqi Zhang, Jingyao Lian, Ling Cao, Feng Li, Lan Huang, Liping Wang, Li Yang, Jianmin Huang, Hong Li, Bin Zhang and Yi Zhang
Pupu Li
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Xinfeng Chen
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Guohui Qin
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Dongli Yue
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Zhen Zhang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Yu Ping
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Dan Wang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Xuan Zhao
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Mengjia Song
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Qitai Zhao
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Jieyao Li
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Shasha Liu
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Dong Wang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Chaoqi Zhang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Jingyao Lian
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Ling Cao
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Feng Li
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Lan Huang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Liping Wang
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Li Yang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Jianmin Huang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Hong Li
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Bin Zhang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
3Department of Hematology/Oncology, School of Medicine, Northwestern University, Chicago, Illinois.
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Yi Zhang
1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
4School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
5Henan Key Laboratory for Tumor Immunology and Biotherapy, Zhengzhou, Henan, China.
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  • For correspondence: yizhang@zzu.edu.cn
DOI: 10.1158/2326-6066.CIR-17-0415 Published October 2018
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ARTICLE USAGE: August 2018 to March 2021

AbstractFull-text HTMLPDF
Total114322781242

Cited By

Article Information

Volume 6, Issue 10, pp. 1246-1259

DOI 
https://doi.org/10.1158/2326-6066.CIR-17-0415
PubMed 
30082413

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received August 7, 2017
  • Revision received January 17, 2018
  • Accepted July 31, 2018
  • Published first August 6, 2018.

Article Versions

  • Previous version (August 6, 2018 - 06:28).
  • Previous version (September 24, 2018 - 06:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2018 American Association for Cancer Research.

Author Information

  1. Pupu Li1,2,
  2. Xinfeng Chen1,2,
  3. Guohui Qin1,2,
  4. Dongli Yue2,
  5. Zhen Zhang1,
  6. Yu Ping1,
  7. Dan Wang1,2,
  8. Xuan Zhao1,
  9. Mengjia Song1,2,
  10. Qitai Zhao1,2,
  11. Jieyao Li2,
  12. Shasha Liu1,
  13. Dong Wang1,2,
  14. Chaoqi Zhang1,2,
  15. Jingyao Lian1,
  16. Ling Cao1,2,
  17. Feng Li1,
  18. Lan Huang1,
  19. Liping Wang2,
  20. Li Yang1,
  21. Jianmin Huang1,
  22. Hong Li1,
  23. Bin Zhang1,3, and
  24. Yi Zhang1,2,4,5,*
  1. 1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
  2. 2Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
  3. 3Department of Hematology/Oncology, School of Medicine, Northwestern University, Chicago, Illinois.
  4. 4School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  5. 5Henan Key Laboratory for Tumor Immunology and Biotherapy, Zhengzhou, Henan, China.
  1. ↵*Corresponding Author:
    Yi Zhang, First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou 450052, Henan, China. Phone: 86-371-66295320; Fax: 86-371-66970906; E-mail: yizhang{at}zzu.edu.cn
  1. P. Li, X. Chen, and G. Qin contributed equally to this article.

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Cancer Immunology Research: 6 (10)
October 2018
Volume 6, Issue 10
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Maelstrom Directs Myeloid-Derived Suppressor Cells to Promote Esophageal Squamous Cell Carcinoma Progression via Activation of the Akt1/RelA/IL8 Signaling Pathway
Pupu Li, Xinfeng Chen, Guohui Qin, Dongli Yue, Zhen Zhang, Yu Ping, Dan Wang, Xuan Zhao, Mengjia Song, Qitai Zhao, Jieyao Li, Shasha Liu, Dong Wang, Chaoqi Zhang, Jingyao Lian, Ling Cao, Feng Li, Lan Huang, Liping Wang, Li Yang, Jianmin Huang, Hong Li, Bin Zhang and Yi Zhang
Cancer Immunol Res October 1 2018 (6) (10) 1246-1259; DOI: 10.1158/2326-6066.CIR-17-0415

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Maelstrom Directs Myeloid-Derived Suppressor Cells to Promote Esophageal Squamous Cell Carcinoma Progression via Activation of the Akt1/RelA/IL8 Signaling Pathway
Pupu Li, Xinfeng Chen, Guohui Qin, Dongli Yue, Zhen Zhang, Yu Ping, Dan Wang, Xuan Zhao, Mengjia Song, Qitai Zhao, Jieyao Li, Shasha Liu, Dong Wang, Chaoqi Zhang, Jingyao Lian, Ling Cao, Feng Li, Lan Huang, Liping Wang, Li Yang, Jianmin Huang, Hong Li, Bin Zhang and Yi Zhang
Cancer Immunol Res October 1 2018 (6) (10) 1246-1259; DOI: 10.1158/2326-6066.CIR-17-0415
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