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Cancer Immunology Research
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Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

Takuro Noguchi, Jeffrey P. Ward, Matthew M. Gubin, Cora D. Arthur, Sang Hun Lee, Jasreet Hundal, Mark J. Selby, Robert F. Graziano, Elaine R. Mardis, Alan J. Korman and Robert D. Schreiber
Takuro Noguchi
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
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Jeffrey P. Ward
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
2Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
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Matthew M. Gubin
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
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Cora D. Arthur
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
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Sang Hun Lee
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
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Jasreet Hundal
3McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri.
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Mark J. Selby
4Bristol-Myers Squibb, Redwood City, California.
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Robert F. Graziano
5Bristol-Myers Squibb, Lawrenceville, New Jersey.
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Elaine R. Mardis
3McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri.
6Department of Genetics, Washington University School of Medicine, St. Louis, Missouri.
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Alan J. Korman
4Bristol-Myers Squibb, Redwood City, California.
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Robert D. Schreiber
1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
7Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, Missouri.
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  • For correspondence: rdschreiber@wustl.edu
DOI: 10.1158/2326-6066.CIR-16-0391 Published February 2017
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Article Information

Volume 5, Issue 2, pp. 106-117

DOI 
https://doi.org/10.1158/2326-6066.CIR-16-0391
PubMed 
28073774

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received December 27, 2016
  • Accepted December 29, 2016
  • Published first January 10, 2017.

Article Versions

  • Previous version (January 10, 2017 - 07:11).
  • Previous version (January 18, 2017 - 06:25).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2017 American Association for Cancer Research.

Author Information

  1. Takuro Noguchi1,
  2. Jeffrey P. Ward1,2,
  3. Matthew M. Gubin1,
  4. Cora D. Arthur1,
  5. Sang Hun Lee1,
  6. Jasreet Hundal3,
  7. Mark J. Selby4,
  8. Robert F. Graziano5,
  9. Elaine R. Mardis3,6,
  10. Alan J. Korman4, and
  11. Robert D. Schreiber1,7,*
  1. 1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.
  2. 2Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  3. 3McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri.
  4. 4Bristol-Myers Squibb, Redwood City, California.
  5. 5Bristol-Myers Squibb, Lawrenceville, New Jersey.
  6. 6Department of Genetics, Washington University School of Medicine, St. Louis, Missouri.
  7. 7Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, Missouri.
  1. ↵*Corresponding Author:
    Robert D. Schreiber, Washington University School of Medicine, 660 South Euclid Avenue, Box 8118, St. Louis, MO 63110. Phone: 1-314-362-8787; E-mail: rdschreiber{at}wustl.edu
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Cancer Immunology Research: 5 (2)
February 2017
Volume 5, Issue 2
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Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape
Takuro Noguchi, Jeffrey P. Ward, Matthew M. Gubin, Cora D. Arthur, Sang Hun Lee, Jasreet Hundal, Mark J. Selby, Robert F. Graziano, Elaine R. Mardis, Alan J. Korman and Robert D. Schreiber
Cancer Immunol Res February 1 2017 (5) (2) 106-117; DOI: 10.1158/2326-6066.CIR-16-0391

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Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape
Takuro Noguchi, Jeffrey P. Ward, Matthew M. Gubin, Cora D. Arthur, Sang Hun Lee, Jasreet Hundal, Mark J. Selby, Robert F. Graziano, Elaine R. Mardis, Alan J. Korman and Robert D. Schreiber
Cancer Immunol Res February 1 2017 (5) (2) 106-117; DOI: 10.1158/2326-6066.CIR-16-0391
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