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Volume 3, Issue 8, pp. 836-843
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- Published first July 8, 2015.
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©2015 American Association for Cancer Research.
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- 1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
- 2Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
- 3Ragon Institute of MGH, MIT and Harvard University, Boston, Massachusetts.
- 4Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
- 5Howard Hughes Medical Institute, Chevy Chase, Maryland.
- ↵*Corresponding Author:
Darrell J. Irvine, MIT, MIT Room 76-261, 77 Massachusetts Avenue, Cambridge, MA 02139. Phone: 617-452-4174; Fax: 617-452-3293; E-mail: djirvine{at}mit.edu
N.K. Mehta and K.D. Moynihan contributed equally to this article.
August 2015
Volume 3, Issue 8
Volume 3, Issue 8
Engineering New Approaches to Cancer Vaccines
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- Article
- Abstract
- Motivation for Cancer Vaccine Engineering
- Targeting Vaccines to Lymph Nodes
- Vaccine-Mediated Programming of T-cell Homing to Tumor Sites
- Exploiting the Tumor Site as an Antigen Source
- Active Depots with Implantable Vaccine Scaffolds
- Conclusions
- Disclosure of Potential Conflicts of Interest
- Grant Support
- References
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