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Cancer Immunology Research
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Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells

Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, Stephanie R. Jackson, Collin L. Chen, Maureen J. Donlin and Ryan M. Teague
Melissa M. Berrien-Elliott
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Jinyun Yuan
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Lauryn E. Swier
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Stephanie R. Jackson
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Collin L. Chen
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Maureen J. Donlin
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
2Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri.
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Ryan M. Teague
1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
3Saint Louis University Cancer Center, St. Louis, Missouri.
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  • For correspondence: rteague@slu.edu
DOI: 10.1158/2326-6066.CIR-14-0159 Published February 2015
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ARTICLE USAGE: December 2014 to February 2021

AbstractFull-text HTMLPDF
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Cited By

Article Information

Volume 3, Issue 2, pp. 116-124

DOI 
https://doi.org/10.1158/2326-6066.CIR-14-0159
PubMed 
25516478

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received August 26, 2014
  • Revision received November 7, 2014
  • Accepted December 8, 2014
  • Published first December 16, 2014.

Article Versions

  • Previous version (December 16, 2014 - 05:54).
  • Previous version (January 22, 2015 - 07:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2014 American Association for Cancer Research.

Author Information

  1. Melissa M. Berrien-Elliott1,
  2. Jinyun Yuan1,
  3. Lauryn E. Swier1,
  4. Stephanie R. Jackson1,
  5. Collin L. Chen1,
  6. Maureen J. Donlin1,2, and
  7. Ryan M. Teague1,3,*
  1. 1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri.
  2. 2Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri.
  3. 3Saint Louis University Cancer Center, St. Louis, Missouri.
  1. ↵*Corresponding Author:
    Ryan M. Teague, Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 South Grand Boulevard, Doisy Research Center Room 705, St. Louis, MO 63104. Phone: 314-977-8871; Fax: 314-977-8717; E-mail: rteague{at}slu.edu
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Cancer Immunology Research: 3 (2)
February 2015
Volume 3, Issue 2
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Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells
Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, Stephanie R. Jackson, Collin L. Chen, Maureen J. Donlin and Ryan M. Teague
Cancer Immunol Res February 1 2015 (3) (2) 116-124; DOI: 10.1158/2326-6066.CIR-14-0159

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Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells
Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, Stephanie R. Jackson, Collin L. Chen, Maureen J. Donlin and Ryan M. Teague
Cancer Immunol Res February 1 2015 (3) (2) 116-124; DOI: 10.1158/2326-6066.CIR-14-0159
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