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Cancer Immunology Research
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Computational Algorithm-Driven Evaluation of Monocytic Myeloid-Derived Suppressor Cell Frequency for Prediction of Clinical Outcomes

Shigehisa Kitano, Michael A. Postow, Carly G.K. Ziegler, Deborah Kuk, Katherine S. Panageas, Czrina Cortez, Teresa Rasalan, Mathew Adamow, Jianda Yuan, Philip Wong, Gregoire Altan-Bonnet, Jedd D. Wolchok and Alexander M. Lesokhin
Shigehisa Kitano
1Department of Experimental Therapeutics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Tsukiji, Tokyo, Japan;
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Michael A. Postow
3Memorial Sloan-Kettering Cancer Center;
4Weill-Cornell Medical and Graduate Schools; and
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Carly G.K. Ziegler
3Memorial Sloan-Kettering Cancer Center;
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Deborah Kuk
3Memorial Sloan-Kettering Cancer Center;
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Katherine S. Panageas
3Memorial Sloan-Kettering Cancer Center;
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Czrina Cortez
3Memorial Sloan-Kettering Cancer Center;
5Ludwig Collaborative and Swim Across America Lab, New York, New York
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Teresa Rasalan
2Ludwig Center for Cancer Immunotherapy;
3Memorial Sloan-Kettering Cancer Center;
5Ludwig Collaborative and Swim Across America Lab, New York, New York
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Mathew Adamow
2Ludwig Center for Cancer Immunotherapy;
3Memorial Sloan-Kettering Cancer Center;
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Jianda Yuan
2Ludwig Center for Cancer Immunotherapy;
3Memorial Sloan-Kettering Cancer Center;
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Philip Wong
2Ludwig Center for Cancer Immunotherapy;
3Memorial Sloan-Kettering Cancer Center;
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Gregoire Altan-Bonnet
3Memorial Sloan-Kettering Cancer Center;
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Jedd D. Wolchok
2Ludwig Center for Cancer Immunotherapy;
3Memorial Sloan-Kettering Cancer Center;
4Weill-Cornell Medical and Graduate Schools; and
5Ludwig Collaborative and Swim Across America Lab, New York, New York
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Alexander M. Lesokhin
3Memorial Sloan-Kettering Cancer Center;
4Weill-Cornell Medical and Graduate Schools; and
5Ludwig Collaborative and Swim Across America Lab, New York, New York
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  • For correspondence: lesokhia@mskcc.org
DOI: 10.1158/2326-6066.CIR-14-0013 Published August 2014
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AbstractFull-text HTMLPDF
Total316434502545

Cited By

Article Information

Volume 2, Issue 8, pp. 812-821

DOI 
https://doi.org/10.1158/2326-6066.CIR-14-0013
PubMed 
24844912

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received January 20, 2014
  • Revision received April 22, 2014
  • Accepted May 12, 2014
  • Published first May 20, 2014.

Article Versions

  • Previous version (May 20, 2014 - 05:48).
  • Previous version (June 30, 2014 - 06:41).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2014 American Association for Cancer Research.

Author Information

  1. Shigehisa Kitano1,
  2. Michael A. Postow3,4,
  3. Carly G.K. Ziegler3,
  4. Deborah Kuk3,
  5. Katherine S. Panageas3,
  6. Czrina Cortez3,5,
  7. Teresa Rasalan2,3,5,
  8. Mathew Adamow2,3,
  9. Jianda Yuan2,3,
  10. Philip Wong2,3,
  11. Gregoire Altan-Bonnet3,
  12. Jedd D. Wolchok2,3,4,5, and
  13. Alexander M. Lesokhin3,4,5,*
  1. Authors' Affiliations: 1Department of Experimental Therapeutics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Tsukiji, Tokyo, Japan;
  2. 2Ludwig Center for Cancer Immunotherapy;
  3. 3Memorial Sloan-Kettering Cancer Center;
  4. 4Weill-Cornell Medical and Graduate Schools; and
  5. 5Ludwig Collaborative and Swim Across America Lab, New York, New York
  1. ↵*Corresponding Author:
    Alexander M. Lesokhin, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065. Phone: 212-639-3069; Fax: 646-227-7116; E-mail: lesokhia{at}mskcc.org
  1. J.D. Wolchok and A.M. Lesokhin contributed equally to this article.

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Cancer Immunology Research: 2 (8)
August 2014
Volume 2, Issue 8
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Computational Algorithm-Driven Evaluation of Monocytic Myeloid-Derived Suppressor Cell Frequency for Prediction of Clinical Outcomes
Shigehisa Kitano, Michael A. Postow, Carly G.K. Ziegler, Deborah Kuk, Katherine S. Panageas, Czrina Cortez, Teresa Rasalan, Mathew Adamow, Jianda Yuan, Philip Wong, Gregoire Altan-Bonnet, Jedd D. Wolchok and Alexander M. Lesokhin
Cancer Immunol Res August 1 2014 (2) (8) 812-821; DOI: 10.1158/2326-6066.CIR-14-0013

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Computational Algorithm-Driven Evaluation of Monocytic Myeloid-Derived Suppressor Cell Frequency for Prediction of Clinical Outcomes
Shigehisa Kitano, Michael A. Postow, Carly G.K. Ziegler, Deborah Kuk, Katherine S. Panageas, Czrina Cortez, Teresa Rasalan, Mathew Adamow, Jianda Yuan, Philip Wong, Gregoire Altan-Bonnet, Jedd D. Wolchok and Alexander M. Lesokhin
Cancer Immunol Res August 1 2014 (2) (8) 812-821; DOI: 10.1158/2326-6066.CIR-14-0013
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