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Cancer Immunology Research
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The Dose-Dependent Tumor Targeting of Antibody–IFNγ Fusion Proteins Reveals an Unexpected Receptor-Trapping Mechanism In Vivo

Teresa Hemmerle and Dario Neri
Teresa Hemmerle
Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zürich), Zürich, Switzerland
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Dario Neri
Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zürich), Zürich, Switzerland
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DOI: 10.1158/2326-6066.CIR-13-0182 Published June 2014
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Volume 2, Issue 6, pp. 559-567

DOI 
https://doi.org/10.1158/2326-6066.CIR-13-0182
PubMed 
24795141

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received October 16, 2013
  • Revision received February 27, 2014
  • Accepted February 28, 2014
  • Published first March 24, 2014.

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  • Previous version (March 24, 2014 - 12:16).
  • Previous version (May 2, 2014 - 07:48).
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Copyright & Usage 
©2014 American Association for Cancer Research.

Author Information

  1. Teresa Hemmerle and
  2. Dario Neri
  1. Authors' Affiliation: Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zürich), Zürich, Switzerland
  1. Corresponding Author:
    Dario Neri, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zürich), Wolfgang-Pauli-Strasse, 10, Zurich 8093, Switzerland. Phone: 41-44-633-74-01; Fax: 41-44-633-13-58; E-mail: neri{at}pharma.ethz.ch
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Cancer Immunology Research: 2 (6)
June 2014
Volume 2, Issue 6
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The Dose-Dependent Tumor Targeting of Antibody–IFNγ Fusion Proteins Reveals an Unexpected Receptor-Trapping Mechanism In Vivo
Teresa Hemmerle and Dario Neri
Cancer Immunol Res June 1 2014 (2) (6) 559-567; DOI: 10.1158/2326-6066.CIR-13-0182

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The Dose-Dependent Tumor Targeting of Antibody–IFNγ Fusion Proteins Reveals an Unexpected Receptor-Trapping Mechanism In Vivo
Teresa Hemmerle and Dario Neri
Cancer Immunol Res June 1 2014 (2) (6) 559-567; DOI: 10.1158/2326-6066.CIR-13-0182
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