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Cancer Immunology Research
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Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

Laura Jeanbart, Marie Ballester, Alexandre de Titta, Patricia Corthésy, Pedro Romero, Jeffrey A. Hubbell and Melody A. Swartz
Laura Jeanbart
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Marie Ballester
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Alexandre de Titta
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Patricia Corthésy
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Pedro Romero
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Jeffrey A. Hubbell
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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Melody A. Swartz
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
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DOI: 10.1158/2326-6066.CIR-14-0019-T Published May 2014
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Total490070315553

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Article Information

Volume 2, Issue 5, pp. 436-447

DOI 
https://doi.org/10.1158/2326-6066.CIR-14-0019-T
PubMed 
24795356

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received January 31, 2014
  • Accepted February 4, 2014
  • Published first February 11, 2014.

Article Versions

  • Previous version (February 11, 2014 - 05:57).
  • Previous version (April 8, 2014 - 06:58).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2014 American Association for Cancer Research.

Author Information

  1. Laura Jeanbart1,2,
  2. Marie Ballester1,2,
  3. Alexandre de Titta1,
  4. Patricia Corthésy1,2,
  5. Pedro Romero4,
  6. Jeffrey A. Hubbell1,3, and
  7. Melody A. Swartz1,2,3
  1. Authors' Affiliations: 1Institute of Bioengineering, School of Life Sciences and School of Engineering; 2Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences; 3Institute for Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL); and 4Ludwig Center for Cancer Research, Université de Lausanne (UNIL), Lausanne, Switzerland
  1. Corresponding Author:
    Melody A. Swartz, Institute of Bioengineering, School of Life Sciences and Engineering, EPFL, SV IBI LLCB, AI 1106, Lausanne, 1015, Switzerland. Phone: 41-21-693-9686; Fax: 41-21-693-9685; E-mail: melody.swartz{at}epfl.ch
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Cancer Immunology Research: 2 (5)
May 2014
Volume 2, Issue 5
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Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes
Laura Jeanbart, Marie Ballester, Alexandre de Titta, Patricia Corthésy, Pedro Romero, Jeffrey A. Hubbell and Melody A. Swartz
Cancer Immunol Res May 1 2014 (2) (5) 436-447; DOI: 10.1158/2326-6066.CIR-14-0019-T

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Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes
Laura Jeanbart, Marie Ballester, Alexandre de Titta, Patricia Corthésy, Pedro Romero, Jeffrey A. Hubbell and Melody A. Swartz
Cancer Immunol Res May 1 2014 (2) (5) 436-447; DOI: 10.1158/2326-6066.CIR-14-0019-T
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