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Cancer Immunology Research
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Research Articles

Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy

Samuel T. Workenhe, Jonathan G. Pol, Brian D. Lichty, Derek T. Cummings and Karen L. Mossman
Samuel T. Workenhe
Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Jonathan G. Pol
Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Brian D. Lichty
Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Derek T. Cummings
Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Karen L. Mossman
Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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DOI: 10.1158/2326-6066.CIR-13-0059-T Published November 2013
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Article Information

Volume 1, Issue 5, pp. 309-319

DOI 
https://doi.org/10.1158/2326-6066.CIR-13-0059-T
PubMed 
24777969

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received May 17, 2013
  • Revision received August 1, 2013
  • Accepted August 12, 2013
  • Published first August 19, 2013.

Article Versions

  • Previous version (August 19, 2013 - 12:24).
  • Previous version (September 23, 2013 - 09:28).
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Copyright & Usage 
©2013 American Association for Cancer Research.

Author Information

  1. Samuel T. Workenhe,
  2. Jonathan G. Pol,
  3. Brian D. Lichty,
  4. Derek T. Cummings, and
  5. Karen L. Mossman
  1. Authors' Affiliation: Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
  1. Corresponding Author:
    Karen L. Mossman, Department of Pathology and Molecular Medicine, 1280 Main Street West, MDCL 5026, Hamilton, Ontario L8S 4K1, Canada. Phone: 905-525-9140, ext. 23542; Fax: 905-522-6750; E-mail: mossk{at}mcmaster.ca
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Cancer Immunology Research: 1 (5)
November 2013
Volume 1, Issue 5
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Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy
Samuel T. Workenhe, Jonathan G. Pol, Brian D. Lichty, Derek T. Cummings and Karen L. Mossman
Cancer Immunol Res November 1 2013 (1) (5) 309-319; DOI: 10.1158/2326-6066.CIR-13-0059-T

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Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy
Samuel T. Workenhe, Jonathan G. Pol, Brian D. Lichty, Derek T. Cummings and Karen L. Mossman
Cancer Immunol Res November 1 2013 (1) (5) 309-319; DOI: 10.1158/2326-6066.CIR-13-0059-T
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