Cancer Immunology
Essentials

Masterful Antibodies: Checkpoint Blockade
Nils Lonberg and Alan J. Korman

Myeloid-Derived Suppressor Cells
George Plitas and Dmitry I. Gabrilovich

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy
Lorenzo Galluzzi, Laurence Zitvogel, and Guido Kroemer

Regulatory T Cells: Differentiation and Function
George Plitas and Alexander Y. Rudensky

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?
Ellen Puré and Albert Lo

Innate Lymphoid Cells in Cancer
Eric Vivier

Neoepitopes of Cancers: Looking Back, Looking Ahead
Pramod K. Srivastava

Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application
Nancy Tray, Jeffrey S. Weber and Sylvia Adams

T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection
Jonathan A. Trujillo, Randy F. Sweis, Riyue Bao and Jason J. Luke

Treg Fragility: A Prerequisite for Effective Antitumor Immunity?
Abigail E. Overacre-Delgoffe and Dario A.A. Vignali

Hallmarks of T-cell Exit from Quiescence
Nicole M. Chapman and Hongbo Chi

Re(de)fining Innate Lymphocyte Lineages in the Face of Cancer
Chun Chou and Ming O. Li

Designing Late-Stage Randomized Clinical Trials with Cancer Immunotherapy: Can We Make It Simpler?
Tai-Tsang Chen

High-Dimensional Profiling of Tumor-Specific Immune Responses: Asking T Cells about What They "See" in Cancer
Evan W. Newell and Etienne Becht

A Blueprint to Advance Colorectal Cancer Immunotherapies
Dung T. Le, Vanessa M. Hubbard-Lucey, Michael A. Morse, Christopher R. Heery, Andrea Dwyer, Thomas H. Marsilje, Arthur N. Brodsky, Emily Chan, Dustin A. Deming, Luis A. Diaz Jr, Wolf H. Fridman, Richard M. Goldberg, Stanley R. Hamilton, Franck Housseau, Elizabeth M. Jaffee, S. Peter Kang, Smitha S. Krishnamurthi, Christopher H. Lieu, Wells Messersmith, Cynthia L. Sears, Neil H. Segal, Arvin Yang, Rebecca A. Moss, Edward Cha, Jill O'Donnell-Tormey, Nancy Roach, Anjelica Q. Davis, Keavy McAbee, Sharyn Worrall, and Al B. Benson