Cancer Immunology
Essentials

CANCER IMMUNOLOGY AT THE CROSSROADS ARCHIVE

2017

Novel “Elements” of Immune Suppression within the Tumor Microenvironment
Devikala Gurusamy, David Clever, Robert Eil, and Nicholas P. Restifo

Inflammasomes and Cancer
Rajendra Karki, Si Ming Man, and Thirumala-Devi Kanneganti

2016

Tumor Microenvironment:
Filling the Tank: Keeping Antitumor T Cells Metabolically Fit for the Long Haul

Greg M. Delgoffe

Complementary Therapeutic Modalities:
Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed

Rasha Abu Eid, Ghazaleh Shoja E. Razavi, Mikayel Mkrtichyan, John Janik, and Samir N. Khleif

Experimental Immunotherapies:
De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute

Ira Mellman, Vanessa M. Hubbard-Lucey, Matthew J. Tontonoz, Michael D. Kalos, Daniel S. Chen, James P. Allison, Charles G. Drake, Hy Levitsky, Nils Lonberg, Sjoerd H. van der Burg, Douglas T. Fearon, E. John Wherry, Israel Lowy, Robert H. Vonderheide, and Patrick Hwu

Tumor Microenvironment:
The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis

Wei Liang and Napoleone Ferrara

2015

Statistical Challenges in the Design of Late-Stage Cancer Immunotherapy Studies
Rosemarie Mick and Tai-Tsang Chen

Experimental Immunotherapies:
Reducing Toxicity of Immune Therapy Using Aptamer-Targeted Drug Delivery

Eli Gilboa, Alexey Berezhnoy, and Brett Schrand

Experimental Immunotherapies:
T-cell–based Immunotherapy: Adoptive Cell Transfer and Checkpoint Inhibition

Roch Houot

Experimental Immunotherapies:
Tumoral Immune Resistance Mediated by Enzymes That Degrade Tryptophan

Nicolas van Baren

Engineering:
Engineering New Approaches to Cancer Vaccines

Naveen K. Mehta

Functional Proteomics:
Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies

Eric B. Haura

Complementary Therapeutic Modalities:
Targeting Heat-Shock Protein 90 (HSP90) as a Complementary Strategy to Immune Checkpoint Blockade for Cancer Therapy

David A. Proia

Complementary Therapeutic Modalities:
The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies

Leisha A. Emens

Experimental Immunotherapies:
The Emerging Understanding of Myeloid Cells as Partners and Targets in Tumor Rejection

Miranda L. Broz

Microbiology:
Microbiota Modulation of Myeloid Cells in Cancer Therapy

Giorgio Trinchieri

Head and Neck Cancer:
Immunity in Head and Neck Cancers

Jonathan D. Schoenfeld

2014

Experimental Immunotherapies:
PD-1 Blockade in Renal Cell Carcinoma: To Equilibrium and Beyond

Lauren C. Harshman

Prostate Cancer Immunotherapy:
Beyond Immunity to Curability for Diagnosis and Treatment

Jonathan W. Simons

Microbiology:
HPV Infection–Associated Cancers: Next-Generation Technology for Diagnosis and Treatment

Cornelia L. Trimble

Complementary Therapeutic Modalites:
Combining Radiation and Immunotherapy: A New Systemic Therapy for Solid Tumors?
James Welsh

Experimental Immunotherapies:
Vaccines For Cancer Prevention: A Practical And Feasible Approach To The Cancer Epidemic

Olivera Finn

Experimental Immunotherapies:
Hostile, Hypoxia–A2-Adenosinergic Tumor Biology as the Next Barrier to Overcome for Tumor Immunologists

Michail V. Sitkovsky

Experimental Immunotherapies:
VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy
Randolph Noelle

Experimental Immunotherapies:
Tim-3: An Emerging Target in the Cancer Immunotherapy Landscape

Ana C. Anderson

Experimental Immunotherapies:
Oncolytic Viruses and Their Application to Cancer Immunotherapy

E. Antonio Chiocca and Samuel D. Rabkin

Experimental Immunotherapies:
IL-10: Master Switch from Tumor-Promoting Inflammation to Antitumor Immunity

Martin Oft

Experimental Immunotherapies:
Killer Immunoglobulin-like Receptors and Tumor Immunity

Don M. Benson Jr. and Michael A. Caligiuri

Microbiology:
Pathogen-Driven Cancers and Emerging Immune Therapeutic Strategies

Paul Nghiem

2013

Public/Private Partnership:
The Melanoma Research Alliance: The Power of Patient Advocacy to Accelerate Research and Novel Therapies

Laura Brockway-Lunardi

Complementary Therapeutic Modalities:
Harnessing the Potential of Radiation-Induced Immune Modulation for Cancer Therapy

Mansoor M. Ahmed

Complementary Therapeutic Modalities:
Temperature Matters! And Why It Should Matter to Tumor Immunologists

Elizabeth A. Repasky

Microbiology:
Microbes and Inflammation in Colorectal Cancer

Wendy S. Garrett

Thoracic Oncology:
Immune Checkpoint Inhibitors: Making Immunotherapy a Reality for the Treatment of Lung Cancer

Drew M. Pardoll

Functional Genomics:
Getting Personal with Neoantigen-Based Therapeutic Cancer Vaccines

Catherine J. Wu