Table 3.

Multivariate analysis for PFS

Multivariate analysis (N = 40)
CovariatesHR (95% CI)P value
Group
 1/2Reference
 3/49.2 (2.5–34.2)<0.001
Use of bevacizumab
 UsedReference
 Not used2.5 (0.7–9.3)0.2
Primary lesion
 Right hemicolonReference
 Left hemicolon0.5 (0.1–1.7)0.3
 Rectum0.5 (0.2–1.7)0.3
IFNγ
 LowReference
 High1.6 (0.6–4.6)0.4
IL8
 LowReference
 High2.7 (0.9–8.7)0.09
  • NOTE: Multivariate analysis for PFS was performed on different immune groups, patient characteristics, and cytokine values by using a Cox proportional hazards model. Covariates were chosen based on the criteria described in Materials and Methods.