Table 2.

Univariate analysis of relationship between m-MDSC and OS at pretreatment baseline and week 6 after ipilimumab

Ipilimumab treated
PretreatmentWeek 6
nHR (95% CI)PnHR (95% CI)P
MDSC < 14.9%680.35 (0.18–0.70)0.002640.38 (0.19–0.75)0.004
ALC ≥ 1,000 cells/μL680.73 (0.41–1.33)0.303640.22 (0.11–0.45)<0.001
LDH < 250680.33 (0.18–0.59)<0.001650.37 (0.20–0.68)0.001
Monocytes < 300 cells/μL680.70 (0.25–1.95)0.495641.77 (0.69–4.51)0.233