Table 3.

Multivariate analysis of relationship between m-MDSC and OS at pretreatment baseline and week 6 after ipilimumab treatment

Ipilimumab
PretreatmentWeek 6
nHR (95% CI)PnHR (95% CI)P
MDSC ≤ 14.9%680.47 (0.23–0.94)0.033630.38 (0.18–0.81)0.012
ALC ≥ 1,000 cells/μL630.21 (0.10–0.46)<0.001
LDH < 250680.38 (0.21–0.69)0.002630.29 (0.15–0.56)<0.001