Table 3.

Correlation of PD-L1 expression by tumor cells with PD-L1 expression by adjacent immune infiltrates in 67 MCC specimens

Tumor PD-L1(−), n (%)Tumor PD-L1+, n (%)a
Tumor sitenTIL PD-L1(−)TIL PD-L1+aTIL PD-L1(−)TIL PD-L1+P valueb
Primary2912 (75)4 (25)0 (0)13 (100)<0.001
Metastasis3821 (95)1 (5)0 (0)16 (100)<0.001
All6733 (87)5 (13)0 (0)29 (100)<0.001
  • aTumor cells or associated infiltrating immune cells were considered PD-L1+ if ≥5% of cells had membranous (cell surface) PD-L1 expression.

  • bFisher exact test.