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Research Article

Calnexin Impairs the Antitumor Immunity of CD4+ and CD8+ T Cells

Yichen Chen, Da Ma, Xi Wang, Juan Fang, Xiangqi Liu, Jingjing Song, Xinye Li, Xianyue Ren, Qiusheng Li, Qunxing Li, Shuqiong Wen, Liqun Luo, Juan Xia, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng and Zhi Wang
Yichen Chen
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Da Ma
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Xi Wang
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Juan Fang
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Xiangqi Liu
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Jingjing Song
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Xinye Li
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Xianyue Ren
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Qiusheng Li
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Qunxing Li
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Shuqiong Wen
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Liqun Luo
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, P.R. China.
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Juan Xia
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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Jun Cui
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, P.R. China.
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Gucheng Zeng
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, P.R. China.
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Lieping Chen
Department of Immunobiology and Yale Comprehensive Cancer Center, Yale University, New Haven, Connecticut.
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Bin Cheng
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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  • For correspondence: wangzh75@mail.sysu.edu.cnchengbin@mail.sysu.edu.cn
Zhi Wang
Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
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  • For correspondence: wangzh75@mail.sysu.edu.cnchengbin@mail.sysu.edu.cn
DOI: 10.1158/2326-6066.CIR-18-0124
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Article Information

DOI 
https://doi.org/10.1158/2326-6066.CIR-18-0124
PubMed 
30401678

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received March 7, 2018
  • Revision received August 6, 2018
  • Accepted November 2, 2018
  • Published first November 6, 2018.

Article Versions

  • Previous version (November 6, 2018 - 07:43).
  • You are currently viewing a Previous version of this article (December 7, 2018 - 07:29).
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Copyright & Usage 
©2018 American Association for Cancer Research.

Author Information

  1. Yichen Chen1,
  2. Da Ma1,
  3. Xi Wang1,
  4. Juan Fang1,
  5. Xiangqi Liu1,
  6. Jingjing Song1,
  7. Xinye Li1,
  8. Xianyue Ren1,
  9. Qiusheng Li1,
  10. Qunxing Li1,
  11. Shuqiong Wen1,
  12. Liqun Luo2,
  13. Juan Xia1,
  14. Jun Cui3,
  15. Gucheng Zeng2,
  16. Lieping Chen4,
  17. Bin Cheng1,*, and
  18. Zhi Wang1,*
  1. 1Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.
  2. 2Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, P.R. China.
  3. 3Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, P.R. China.
  4. 4Department of Immunobiology and Yale Comprehensive Cancer Center, Yale University, New Haven, Connecticut.
  1. ↵*Corresponding Authors:
    Zhi Wang, Sun Yat-Sen University, No. 56, Lingyuanwest Road, Guangzhou 510055, Guangdong, China. Phone: 8620-8733-0591; Fax: 8620-8382-2807; E-mail: wangzh75{at}mail.sysu.edu.cn; and Bin Cheng, chengbin{at}mail.sysu.edu.cn
  1. Y. Chen, D. Ma, and X. Wang contributed equally to this article.

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Published OnlineFirst December 7, 2018
doi: 10.1158/2326-6066.CIR-18-0124

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Calnexin Impairs the Antitumor Immunity of CD4+ and CD8+ T Cells
Yichen Chen, Da Ma, Xi Wang, Juan Fang, Xiangqi Liu, Jingjing Song, Xinye Li, Xianyue Ren, Qiusheng Li, Qunxing Li, Shuqiong Wen, Liqun Luo, Juan Xia, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng and Zhi Wang
Cancer Immunol Res December 7 2018 DOI: 10.1158/2326-6066.CIR-18-0124

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Calnexin Impairs the Antitumor Immunity of CD4+ and CD8+ T Cells
Yichen Chen, Da Ma, Xi Wang, Juan Fang, Xiangqi Liu, Jingjing Song, Xinye Li, Xianyue Ren, Qiusheng Li, Qunxing Li, Shuqiong Wen, Liqun Luo, Juan Xia, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng and Zhi Wang
Cancer Immunol Res December 7 2018 DOI: 10.1158/2326-6066.CIR-18-0124
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