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Research Article

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells

Angelamaria Rizzo, Martina Di Giovangiulio, Carmine Stolfi, Eleonora Franzè, Hans-Joerg Fehling, Rita Carsetti, Ezio Giorda, Alfredo Colantoni, Angela Ortenzi, Massimo Rugge, Claudia Mescoli, Giovanni Monteleone and Massimo C Fantini
Angelamaria Rizzo
Internal Medicine, University of Rome Tor Vergata
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  • ORCID record for Angelamaria Rizzo
Martina Di Giovangiulio
Systems Medicine, University of Rome Tor Vergata
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Carmine Stolfi
Systems Medicine, University of Rome Tor Vergata
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Eleonora Franzè
Internal Medicine, University of Rome Tor Vergata
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Hans-Joerg Fehling
Institute of Immunology, University Clinics Ulm
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Rita Carsetti
Cytofluorimetry Laboratory, Bambino Gesù Pediatric Hospital
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Ezio Giorda
Research Center, Ospedale Bambino Gesù
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Alfredo Colantoni
Systems Medicine, University of Rome Tor Vergata
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Angela Ortenzi
Systems Medicine, University of Rome Tor Vergata
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Massimo Rugge
Department of Medicine-DIMED, University of Padua
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Claudia Mescoli
Department of Medicine DIMED Pathology and Cytopathology Unit, University of Padova
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Giovanni Monteleone
Systems Medicine, University of Rome Tor Vergata
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Massimo C Fantini
Systems Medicine, University of Rome Tor Vergata
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  • For correspondence: m.fantini@med.uniroma2.it
DOI: 10.1158/2326-6066.CIR-17-0698
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Article Information

DOI 
https://doi.org/10.1158/2326-6066.CIR-17-0698
PubMed 
29991500

Published By 
American Association for Cancer Research
Print ISSN 
2326-6066
Online ISSN 
2326-6074
History 
  • Received December 2, 2017
  • Revision received April 17, 2018
  • Accepted July 5, 2018
  • Published first July 10, 2018.

Article Versions

  • You are currently viewing a Previous version of this article (July 10, 2018 - 06:44).
  • Previous version (August 7, 2018 - 06:00).
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Copyright & Usage 
Copyright ©2018, American Association for Cancer Research.

Author Information

  1. Angelamaria Rizzo1,
  2. Martina Di Giovangiulio2,
  3. Carmine Stolfi2,
  4. Eleonora Franzè1,
  5. Hans-Joerg Fehling3,
  6. Rita Carsetti4,
  7. Ezio Giorda5,
  8. Alfredo Colantoni2,
  9. Angela Ortenzi2,
  10. Massimo Rugge6,
  11. Claudia Mescoli7,
  12. Giovanni Monteleone2, and
  13. Massimo C Fantini2,*
  1. 1Internal Medicine, University of Rome Tor Vergata
  2. 2Systems Medicine, University of Rome Tor Vergata
  3. 3Institute of Immunology, University Clinics Ulm
  4. 4Cytofluorimetry Laboratory, Bambino Gesù Pediatric Hospital
  5. 5Research Center, Ospedale Bambino Gesù
  6. 6Department of Medicine-DIMED, University of Padua
  7. 7Department of Medicine DIMED Pathology and Cytopathology Unit, University of Padova
  1. ↵* Corresponding Author:
    Massimo C Fantini, Systems Medicine, University of Rome Tor Vergata, Rome, 00137, Italy. E-mail: m.fantini{at}med.uniroma2.it

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Published OnlineFirst July 10, 2018
doi: 10.1158/2326-6066.CIR-17-0698

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RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells
Angelamaria Rizzo, Martina Di Giovangiulio, Carmine Stolfi, Eleonora Franzè, Hans-Joerg Fehling, Rita Carsetti, Ezio Giorda, Alfredo Colantoni, Angela Ortenzi, Massimo Rugge, Claudia Mescoli, Giovanni Monteleone and Massimo C Fantini
Cancer Immunol Res July 10 2018 DOI: 10.1158/2326-6066.CIR-17-0698

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RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells
Angelamaria Rizzo, Martina Di Giovangiulio, Carmine Stolfi, Eleonora Franzè, Hans-Joerg Fehling, Rita Carsetti, Ezio Giorda, Alfredo Colantoni, Angela Ortenzi, Massimo Rugge, Claudia Mescoli, Giovanni Monteleone and Massimo C Fantini
Cancer Immunol Res July 10 2018 DOI: 10.1158/2326-6066.CIR-17-0698
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